Description
Product Characteristics: This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance.,TRHR,TRH-R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),TRHR
Target Information: regulates thyroid gland function\, mediates phospholipase C activation and increased intracellular calcium [RGD, Feb 2006]